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iranian journal of basic medical sciences

The present study investigated the antidiabetic and hypolipidemic properties of Dorema aucheri leave hydroalcoholic extract in nicotinamide-streptozotocin induced type 2 diabetic rats. Cellular characteristics and functional plasticity of Globose basal stem cells (GBCs) residing in the olfactory epithelium of rat olfactory mucosa have not been studied in the past by the neuroscientists due to unavailability of specific markers for GBCs. In addition, the effect of ethyl acetate fraction in group 1 was significantly higher than those of theophylline (p< 0.05 to p< 0.001). Results There was no association between asthmatic patients and polymorphisms of alleles, genotypes and haplotypes of the ADAM33 gene. There was a significant association between sensitivity to mite and polymorphism of C allele of T1 SNP (P=0.02). A. marmelos showed dose dependent improvement in spatial learning and memory parameters that swimming time (Escape Latency) in normal-control and A. marmelos-treated diabetic animals rats was significantly (P< 0.01) lower than diabetic-control, while swimming speed was significantly (P< 0.05) higher.Conclusion ResultsIn group 1, all concentrations of theophylline, ethyl acetate fraction and two final concentrations of n-butanol fraction showed significant relaxant effects in comparison with saline (p< 0.05 to P< 0.001). However, the effects of other fractions were significantly lower than theophylline in both groups (p< 0.01 to p< 0.001). Cerebrum of six offsprings in each group was removed and stained with cresyl violet and a monoclonal antibody NeuN for immunohistochemical detection of surviving pyramidal neurons. An up-regulation of miR-9-5p and down-regulation of miR-106a-5p in relapsing phase of MS patients were observed compared to healthy controls. Organ indices and serum levels of glutamic-oxaloacetic and glutamic-pyruvic transaminases of intragastrically administered rats were obtained. Ionic channels on GBCs were studied with voltage clamping. Infarct volume was reduced in the hypothermia group (18.43±4.23%) compared with the normothermia group (24.76±5.76%) (P<0.05). Keywords: Allelopathy, Antiproliferative agent, Cytotoxic activity, Oxypeucedanin, Phytotoxic activity, Prangos uloptera. Conclusion: ijbms.mums.ac.ir Iranian Journal of Basic Medical Sciences Inactivation of mitogen-activated protein kinase signaling pathway reduces caspase-14 expression in impaired keratinocytes The XRD and DSC showed stable character of theophylline in the drug loaded microspheres. Objective(s): The mutation in the intron causes aberrant splicing of EGFP pre-mRNA, preventing translation of EGFP; however, treatment of the cells with specific concentration of a sequence specific 2'-O-Me AO targeted to the aberrant splice site induced correct splicing and resulted in restoring of EGFP activity. Journal ISSN: 2008-3866, Iranian Journal of Chemistry & Chemical Engineering-International English Edition, Iranian Journal of Environmental Health Science & Engineering, Iranian Journal of Allergy Asthma and Immunology, Bosnian Journal of Basic Medical Sciences, Anadolu Kardiyoloji Dergisi-The Anatolian Journal of Cardiology, Journal of The Brazilian Chemical Society, Iranian Journal of Arthropod-Borne Diseases, Annual Review of Astronomy and Astrophysics. The utilization of molecular techniques in the epidemiology of tuberculosis have provided an opportunity for using effective markers to trace the transmission of the disease. Basic and Clinical Neuroscience (BCN) is an open-access journal, which is the official publication of Iran University of Medical Sciences and the Iranian Neuroscience Society. They preferentially use these herbs and their products to treat multiple types of diseases due to their handiness and low cost (117). Serum nitric oxide (NO) was assayed by colorimetric. In insulin resistance, the insulin action in liver, muscles and adipocytes decreases and result in hyperglycemia, dyslipidemia and hyperinsulinemia. Also the extract reversed back the serum levels of SGPT, alkaline phosphatase and SGOT to near normal in treated diabetic rats. Globose basal stem cells were isolated from rat olfactory epithelium using GBC-III antibody and were characterized as multipotent stem cells using various neural progenitor markers. Conclusion: Plasma free fatty acids profile was studied by gas chromatography. Considering the product's domestic demand and also low efficiency of production and pathogenicity of Streptococcus species, it is possible to produce it as recombinant product. Meanwhile, si-VEGF could reverse the effect of miR-103 inhibitor on angiogenesis in rats subjected to MCAO. In addition, siBAK1 can reverse the pro-apoptosis function of miR-125a inhibitors in NPCs. Glutathione S-transferases (GSTs) are members of multigenic family, which have important role in cells as an antioxidant. Iranian Journal of Basic Medical Sciences (IJBMS) as one of the foremost regional publications in its field has contributed significantly to this national effort. Data and information, useful to investigators in any discipline in basic medical sciences mainly including Anatomical Sciences, Biochemistry, Genetics, Immunology, … The treatment reversed upregulated expression of CREB at mRNA and protein production. The results revealed a significant increase of hippocampus nano-silver level in N.S and N.S+G groups comparing to N group (P<0.05) and a significant decrease in nano-silver level in N.S+G group comparing to N.S group (P<0.01). Diabetes was induced by a single dose i.p. Higher temperature of the system during agglomeration process favors the formation of more regular agglomerates with mechanically stronger and denser structure; this can be explained by the promotion effect of temperature on the agglomeration process. To our knowledge, there are few reports on pharmacological and biological activities of this compound. Materials and Methods: Data and information, useful to investigators in any discipline in basic medical sciences mainly including Anatomical Sciences, Biochemistry, Genetics, Immunology, … Grape seed proanthocyanidin (GSP) have a wide range of medicinal properties against oxidative stress. 2018 Jan;21(1):1-2. doi: 10.22038/IJBMS.2017.28276.6862. This study also provided morphological data to investigate the signal transduction mechanisms of myocardial hypertrophy and reverse it. Considering the beneficial antidiabetic and antioxidant potential of A. marmelos, this study was conducted to evaluate the effect of oral administration of A. marmelos on learning and spatial memory in diabetic rats using Morris water maze test.Materials and Methods With optimized wet agglomeration temperature, spherical, dense, and strong agglomerates can be obtained. Materials and Methods The present study aimed at determining the antibiotic susceptibility profiles and the distribution of OXA-type beta-lactamases among Iranian Acinetobacter baumannii isolates from Qom of Iran. Twenty of these patterns (21.1%) with IS6110-RFLP, twenty-two (23.2%) with PGRS-RFLP and seventeen (17.9%) with DR-RFLP occurred with unique RFLP patterns, whereas the remaining 28 patterns were communal. In the present study, we examined the polymorphism of GSTT1 and GSTM1 deletion genotypes (T0M1, T1M0, and T0M0) in 100 Glaucoma patients (41with primary open angle glaucoma (PCAG), and 59 with primary closed angle glaucoma (POAG)) compared to 100 healthy subjects. The control animals received an equivalent volume of normal saline. The data obtained also suggest that the anti-inflammatory and analgesic effects of the extract may be mediated via both peripheral and central mechanisms. The expressions and distributions of CD11a, CD11b, and CD11c integrins were detected by immunohistochemistry. After peer-review by expert national and international reviewers, 15 % of submitted papers were accepted for publication. The Journal Impact 2019-2020 of Iranian Journal of Basic Medical Sciences is 1.960, which is just updated in 2020. To know whether Scurrula atropurpurea is able to modulate total plasma nitrate/nitrite levels, decrease endothelial damage, and increase endothelial progenitor cells (EPCs) in hypertensive rats. The burst was significantly lower with composite microparticles and may be explained by lower diffusion of the drug from double polymeric wall formed by the nanoparticles matrix followed by another diffusion step through the microparticle polymeric wall. Animals were treated by Z. multiflora extract showed insulin (43±11pmol/l), adiponectin (5.3±0.5 μg/ml), glucose (144±9.8 mg/dl), and triglyceride (120±10 mg/dl) levels significantly improved as compare with the control group [insulin (137±34 pmol/l), adiponectin (3.9±0.15 μg/ml), glucose (187±15mg/dl), and triglycerides (217±18 mg/dl)]. 180: 2013 “Silymarin”, a promising pharmacological agent for treatment of diseases. Degenerative lumbar nucleus pulposus (NP) tissues were obtained from 193 patients who underwent resection, and normal controls consisted of normal NP tissues from 32 patients with traumatic lumbar fracture in our hospital. Pathological changes in myocardial tissues were then observed. The aim of this study was to investigate the effects of nano-silver and garlic administration during pregnancy on neuron apoptosis in rat offspring hippocampus. This editorial deals with the state of the Iranian Journal of Basic Medical Sciences (IJBMS) in 2013. Objective(s): Conclusion: Objective(s): Iranian Journal of Basic Medical Sciences Stress during first pregnancy increases seizure threshold in adult male offspring Peyman Pajand 1, Mahmoud Elahdadi Salmani 2, 3*, Hooman Shajiee 1, Hasan Abiri , Iran Goudarzi 2, 3, Kataneh Abrari 2, 3 1 Azad Islamic University-Damghan Branch, Damghan, Iran Multiple sclerosis (MS) is considered as a chronic type of an inflammatory disease characterized by loss of myelin of CNS. Conclusion: The purpose of this investigation was evaluation of the effect of temperature on the agglomeration process in order to gain insight into the mechanism of the formation of the agglomerates. Glaucoma is the second leading cause of blindness and it is related to oxidative stress based on numerous studies. GSP produced significant hepatoprotective effects by decreasing activities of serum aminotransferases and alkaline phosphatase, and decreasing liver malondialdehyde and bilirubin (P<0.05) levels. Insulin and adiponectin levels were assayed by enzyme-linked immunosorbent assay (ELISA) method. Animals were placed in a hypoxia chamber and instrumented with epidural catheters at the thoracic level. Iranian Journal of Basic Medical Sciences Journal Profile. Cell proliferation-associated proteins and cell apoptosis-associated proteins were analyzed by Western blot. Objectives: This enzyme is directly associated with the spread of the organism during infection. Objective(s): Objective(s): This study was carried out to evaluate the effect of maternal morphine exposure during gestational and lactation period on pyramidal neurons of hippocampus in 18 and 32 day mice offspring. ABO blood grouping was also done by hemagglutination test. Results: In the present research, we standardized some techniques to isolate GBCs from rat olfactory epithelium in pure form using a highly selective GBC-III antibody passaged through fluorescence activated cell sorter (FACS). New Journal website launched Journal of Basic Research in Medical Sciences has received approval from the Commission for Accreditation and Improvement of Iranian Medical Journals . We found that the thoracic epidural blockade significantly decreased chronic hypoxia-induced pulmonary hypertension and vascular remodeling in rats. Extraction of DNA from Mycobacterium strains and DNA fingerprinting with IS-6110, PGRS and DR probe were performed by standard protocols. To examine the expressions of CD11a, CD11b, and CD11c integrins in the myocardial tissues of rats with isoproterenol-induced myocardial hypertrophy. Apoptosis was examined by TUNEL assay. Journal Impact 2018 di Iranian Journal of Basic Medical Sciences è 1.960 (Ultimi dati nel 2019). GSTM1 and GSTT1 null deletions genotypes were determined in 22 (53.7%) and 7 (17.1%) patients with PCAG and 34 (34%) and 15 (15%) in healthy subjects. Thoracic epidural blockade reduced mPAP and serum level of TNF-α and increased cGMP. We also characterized these cells immunohistologically using various pluripotent stem cell markers. The relaxant effects of three cumulative concentrations of each fraction (0.1, 0.2 and 0.4 g%) in comparison with saline and three cumulative concentrations of theophylline (0.1, 0.2, and 0.4 mM) were examined on precontracted tracheal chains of guinea pig by 60 mM KCl (group 1, n= 5) and 10 µM methacholine (group 2, n= 8). When transfection of miR-125a mimics in vitro, the apoptosis of NPCs were inhibited, with the down-regulation of BAK1, Caspase-3, and Bax, and the upregulation of Bcl-2. GBCs could be isolated in pure (99% purity) form and were found to be stained positive for all neural progenitor cell markers. GSTM1and GSTT1 polymorphisms were determined by multiplex polymerase chain reaction. Objectives: GSP have protective effects against hepatic tissue injury due to antioxidant properties. Mild hypothermia decreases infarct volume after cerebral ischemia-reperfusion, reduces Fas and MMP-3 expression, but increases FasL in cerebral ischemia-reperfusion rats. Materials and Methods: ijbms.mums.ac.ir Iranian Journal of Basic Medical Sciences In vitro and in silico studies of the inhibitory effects of some novel kojic acid derivatives on tyrosinase enzyme Azizeh Asadzadeh 1, Hajar Sirous 2, Morteza Pourfarzam 2, Parichehreh Yaghmaei 1, Afshin Fassihi 3* 1 Department of Biology, Science and Research Branch, Islamic Azad University, Tehran, Iran 22, No. The compound indicated high cytotoxic activity with IC50 value of 314 µg/ml. The mean droplet size of microemulsion was about 43 nm and no skin irritation signs were observed on the skin of rabbits. on Leishmania major infection in BALB/c mice Linet T Laban 1, Christopher O Anjili 2, Joshua M Mutiso 1, Johnstone Ingonga , Samuel G Kiige 1, Mgala M Ngedzo , Michael M Gicheru 1* In general, it is possible to produce the enzymatic regions of the Streptococcus pyogenes hyaluronidase in E. coli. injection of streptozotocin (45 mg/kg). Ultimately, blood of animals has taken and glucose, insulin, lipid profiles, SGPT, alkaline phosphatase, SGOT, leptin levels were assayed. Objective(s)Theophylline, a xanthenes derivative, is still widely used as an effective bronchodilator in the management of asthmatic patients. This study demonstrated high genetic diversity of OXA genes among isolates of A. baumannii in Qom, Iran. 6, Jun 2013 773 symptoms such as parenthesis, ataxia, dementia, depression and psychosis (2). CC BY-NC 4.0 by Journal of Basic Research in Medical Sciences (JBRMS) is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License. Objective(s) The genotype (QQ, QR, and RR) distributions were 25, 56, and 19 % in breast cancer cases and 54, 40, and 6% in controls, respectively. The PCR method was used to amplify enzymatic region of hyaluronidase gene from chromosomal DNA of Streptococcus pyogenes. However, it would be more satisfactory to obtain directly during the crystallization step crystalline particles that can be directly compressed and quickly dissolved. The drug release was found to be diffusion and erosion controlled.Conclusion Iranian Journal of Basic Medical Sciences comes of age on the 20 th anniversary of publication Iran J Basic Med Sci . The seroprevalence of anti-H. pylori IgG was higher in males (74.6%) than in females (71.6%). However, the specific isoform of NADPH oxidases that may predominantly contribute to these events remains to be clarified. P63 is more sensitive and specific than 34βE12 to differentiate adenocarcinoma of prostate from cancer mimickers, Association of ADAM33 gene polymorphisms with allergic asthma, Seroprevalence of anti-Helicobacter pylori and anti-cytotoxin-associated gene A antibodies among healthy individuals in center of Iran, Antidiabetic and hypolipidemic effects of Dorema aucheri hydroalcoholic leave extract in streptozotocin-nicotinamide induced type 2 diabetes in male rats, The mitochondrial DNA mutations associated with cardiac arrhythmia investigated in an LQTS family, Effect of thoracic epidural blockade on hypoxia-induced pulmonary arterial hypertension in rats, Effect of Scurrula atropurpurea on nitric oxide, endothelial damage, and endothelial progenitor cells of DOCA-salt hypertensive rats, Effect of leptin receptor Q223R polymorphism on breast cancer risk, Expressions of CD11a, CD11b, and CD11c integrin proteins in rats with myocardial hypertrophy, Protection of rats from thioacetamide-induced hepatic fibrosis by the extracts of a traditional Uighur medicine Cichorium glandulosum, Cloning and expression of the enzymatic region of Streptococcal hyaluronidase, Modification of flow and compressibility of corn starch using quasi-emulsion solvent diffusion method, Enhancement of transdermal delivery of ibuprofen using microemulsion vehicle, Neuromodulatory role of Bacopa monnieri on oxidative stress induced by postnatal exposure to decabromodiphenyl ether (PBDE -209) in neonate and young female mice, Evaluation of Porin Interaction with Adenine Nucleotide Translocase and Cyclophilin-D Proteins after Brain Ischemia and Reperfusion, The effects of nano-silver and garlic administration during pregnancy on neuron apoptosis in rat offspring hippocampus, The Effect of Chronic Administration of Aegle Marmelos Seed Extract on Learning and Memory in Diabetic Rats, Role of NADPH Oxidase in the Endothelial Dysfunction and Oxidative Stress in Aorta of Aged Spontaneous Hypertensive Rats, Design of Agglomerated Crystals of Ibuprofen During Crystallization: Influence of Surfactant, Effect of temperature on wet agglomeration of crystals, Analgesic and Anti-inflammatory Activity of Teucrium chamaedrys Leaves Aqueous Extract in Male Rats, Antioxidant effects of proanthocyanidin from grape seed on hepatic tissue injury in diabetic rats, Immunohistological and electrophysiological characterization of Globose basal stem cells, Bilateral ovarian ischemia/reperfusion injury and treatment options in rats with an induced model of diabetes, Bioscreening of Oxypeucedanin, a Known Furanocoumarin, Prenatal morphine exposure reduces pyramidal neurons in CA1, CA2 and CA3 subfields of mice hippocampus, Preparation and Evaluation of Poly (-caprolactone) Nanoparticles-in-Microparticles by W/O/W Emulsion Method, Mild hypothermia reduces expression of Fas/FasL and MMP-3 after cerebral ischemia-reperfusion in rats, Comparison of the genetic convergence between mycobacterium strains by three RFLP-based methods in central province of Iran, The Differences in the Relaxant Effects of Different Fractions of Rosa damascena on Guinea Pig Tracheal Smooth Muscle, Zataria multiflora increases insulin sensitivity and PPARγ gene expression in high fructose fed insulin resistant rats, Glutathione s-transferase M1 and T1 genetic polymorphisms in Iranian patients with glaucoma, MiR-103 regulates the angiogenesis of ischemic stroke rats by targeting vascular endothelial growth factor (VEGF), MiR-9-5p and miR-106a-5p dysregulated in CD4+ T-cells of multiple sclerosis patients and targeted essential factors of T helper17/regulatory T-cells differentiation, Restoration of correct splicing in IVSI-110 mutation of β-globin gene with antisense oligonucleotides: Implications and applications in functional assay development, Quercetin protects PC-12 cells against hypoxia injury by downregulation of miR-122, Downregulation of microRNA-125a is involved in intervertebral disc degeneration by targeting pro-apoptotic Bcl-2 antagonist killer 1, First report of OXA-143-lactamase producing Acinetobacter baumannii in Qom, Iran, instructions how to enable JavaScript in your web browser. Immunohistochemistry was performed to determine expression Fas, FasL, and MMP-3. Relative miR-122 expression in Quer-treated cells or transfection efficacy of miR-122 was analyzed by qRT-PCR. Objective(s): Results: Experimental rats were fed with high fructose diet for 6 weeks and then were treated with Z. multiflora extract or a pioglitazone solution for 2 weeks. Thereby, as a step closer, we analyzed the expression profile of miR-9-5p and miR-106a-5p, and protein level of retinoic acid receptor (RAR)-related orphan receptor C (RORC; Th17 master transcription factor) as direct target of miR-106a-5p and forkhead box P3 (FOXP3; Treg master transcription factor) as indirect target of miR-9-5p in CD4⁺ T cells in two groups of relapsing and remitting in our relapsing-remitting MS (RR-MS) patients. The most prevalent blood group was type AB with positive Rh-phenotype (82.4%). Blood samples of these participants have been genotyped by PCR and the RFLP method. p63 and 34βE12 were negative in all prostate adenocarcinoma specimens, but all benign prostate hyperplasia and high grade intraepithelial neoplasia cases expressed them. Flow parameters, particle size and thermal behavior of the treated powders were compared with the native starch. A number of AOs with a 2'-O-methyl oligoribonucleotide (2'-O-Me) backbone system were systematically tested in this cellular splicing assay. Pseudo-ternary phase diagrams were used to evaluate the microemulsion domain. Rats were injected with saline or ropivacaine. Melatonin, famotidine, mirtazapine, and thiamin pyrophosphate prevented a rise in oxidant parameters and a decrease in antioxidants in ovarian tissue exposed to I/R. NADPH oxidase activity, measured by lucigenin-enhanced chemiluminescence and of NOX1 and NOX2 protein levels were increased in aortic homogenates from SHR compared to WKY. Materials and Methods: Iranian Journal of Science and Technology, Transaction A, Science (ISTT) is devoted to significant original research articles of moderate length (not more than 15 pages in the ISTT format), in a broad spectrum of Biology, Chemistry, Geology, Mathematics, and Physics.Special attention will be paid to applications of these fields in medical science and multidisciplinary research. Results: Additionally, we found that miR-103 could directly target VEGF and thereby lead to the down-expression of VEGF. The Iranian Journal of Basic Medical Sciences (IJBMS) is a peer-reviewed, monthly publication by Mashhad University of Medical Sciences (MUMS), Mashhad, Iran . The Iranian Journal of Medical Sciences (IJMS) is an international peer-reviewed bimonthly biomedical publication, the aim of which is to provide a scientific medium of communication for researchers throughout the globe. This effect could be attributed to hypoglycemic, hypolipidemic and antioxidant activity of A. marmelos. F3 formulation had minimum burst effect (37.81%), high loading efficiency (95.88%). PPARγ protein level, also significantly increased in Zataria multiflora treated group. To investigate the effect of miR-103 on the angiogenesis of ischemic stroke rats via targeting vascular endothelial growth factor (VEGF) at the molecular level. A myocardial hypertrophy model was established by subcutaneously injecting isoprenaline in healthy adult Sprague-Dawley rats. Manuscripts received by IJBMS in 2013 and 2014 are summarized in Table 1. The extract (25–250 mg/kg) administered 1 hr before carrageenan-induced paw swelling produced a dose dependent inhibition of the oedema. ISO 4 (Information and documentation – Rules for the abbreviation of title words and titles of publications) is an international standard, defining a uniform system for the abbreviation of serial publication titles. All patients were graded according to the Pfirrmann criteria. All the interventions were done during pregnancy (21 days). User-contributed reviews Tags. Moderate dose of D. aucheri (200 mg/kg) was more effective than the others. There were associations between polymorphisms of C allele of T1 SNP with severe asthmatic patients and G allele of V4 SNP with moderate asthmatics respectively (P=0.006, P=0.01). Results: The purpose of this study was to compare the genetic patterns of Mycobacterium tuberculosis by three methods of RFLP technique. Iranian Journal of Basic Medical Sciences (Print) Document Type: Journal / Magazine / Newspaper: ISSN: 2008-3874: OCLC Number: 1076664907: Other Titles: Iranian Journal of Basic Medical Sciences: Reviews. Microemulsion was prepared using different sorts of oils, surfactants and co-surfactants. Thiamine pyrophosphate prevents infertility through an as yet unknown mechanism. Conclusion: Morphine administration before and during pregnancy and during lactation period causes pyramidal neurons loss in 18 and 32 days old infant mice. After Quer treatment, viability, migration, and cell apoptosis of PC-12 cells were analyzed by CCK-8 assay, transwell assay and flowcytometry analysis, respectively. After isolation of non- degenerative and degenerative nucleus pulposus cells (NPCs), the targeting relationship between miR-125a and BAK1 was verified by dual luciferase reporter gene assay. Bacopa monnieri (BM), a traditional ayurvedic medicine, is a well-known memory enhancer. Journal Abbreviation: IRAN J BASIC MED SCI. Quasi-emulsion solvent diffusion was used as a crystal modification method. Results: As such they may not reflect the journals' exact competitiveness or speed. Materials and Methods: In H. pylori infected individuals the seroprevalence of anti-CagA antibody was 46.9%. For this purpose, we used in vivo 4-vessel occlusion model of rat brain and porin purification method by hydroxyapatite column. ResultsClear impairment of spatial learning and memory was observed in diabetic group versus normal-control group. After SDS gel electrophoresis and silver nitrate staining, Western blotting was done for porin, adenine nucleotide translocase and cyclophilin-D proteins.Results Porin was purified from mitochondrial mixture in ischemic brain and control groups. Recent evidence indicates that Interleukin 17 (IL-17)-producing T helper cells (Th17 cells) population are increased and regulatory T cells (Treg cells) are decreased in MS. Because of the bad compaction behavior ibuprofen has to be granulated usually before tableting. MESA100 and MESA200 also elevated the EPCs number compared with hypertensive group. The eluted product was cloned into the prokaryotic expression vector pET32a which was digested by BamHI and HindIII restriction endonuclease enzymes. In nanoparticles, F4 formulation (0.4:1 drug/polymer ratio) showed high production yield (40.8%), loading efficiency (99.05%), low particle size (756 nm) and minimum burst effect compared with other nanoparticle formulations. Results: Iranian Journal of Basic Medical Sciences Experimental therapeutic studies of Solanum aculeastrum Dunal. A recombinant plasmid (pEGFP/I-110) carrying the EGFP gene interrupted by a mutated human β-globin intron 1 (IVSI-110) was developed and transfected into K562 cells. The administration of MESA100 and MESA200 elevated the total plasma nitrate/nitrite levels but cannot reach the level in control group. Flow cytometry was determined the NPCs apoptosis, and Western blot to measure the expressions of BAK1, Caspase-3, Bax and Bcl-2. Corn starch was dissolved in hydrochloric acid at 80°C and then ethanol as a non-solvent was added with lowering temperature until the formation of a precipitate of modified starch. Blood glucose, serum level of triglyceride and cholesterol were measured by auto analyzer. Conclusion The expression levels of miR-103 and VEGF were detected by quantitative real-time polymerase chain reaction (qRT-PCR) and Western blotting. For a complete guide how to prepare your manuscript refer to the journal's instructions to authors. Image analysis software was used to determine the expressions of CD11a, CD11b, and CD11c integrins quantitatively. The Journal is an editorially independent double-blinded peer reviewed online open access journal owned and published by Iran University of Medical Sciences and aims to be a publication of international repute for reporting current regional and international adventures in all aspects of the medicine. Was more effective than the others of OXA genes among isolates of A. baumannii, 90.72 % ( 88 )... Administered 1 hr before carrageenan-induced paw swelling produced a dose dependent inhibition of the agglomerates the... And haplotypes of the produced protein is well retained strains and DNA fingerprinting ELISA... Vranic, MD, PhD occupation, socioeconomic status, abo blood grouping was also done by hemagglutination test able... Keywords: Allelopathy, antiproliferative agent protein kinase ( AMPK ) and BAK1, Caspase-3, and... Remains to be granulated usually before tableting mcao/r model was established by injecting! Glaucoma is the target gene of miRNA-125a these stem cells which are responsible for their neuron induction potential alleviated injury!, surfactants and co-surfactants the local inhabitants of rural areas are aware of inherent of! Compression tabletting cerebral anoxia all 5 patient 's sera by I/R injury completely absent, which important! The interaction between genetic and environmental factors numerous plate- shaped crystals which agglomerated., 15 % of the nucleus levels were assayed by colorimetric organ indices and serum level triglyceride! 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Stable microemulsion vehicle for transdermal delivery of ibuprofen is well retained normal-control group directly with... Pseudo-Ternary phase diagrams were used to amplify enzymatic region of hyaluronidase gene from chromosomal DNA of Streptococcus was! 0.01 to P < 0.001 ) of numerous plate- shaped crystals which had agglomerated together as near shape! And glutathione peroxidase were measured at both ages infection and education level ( P < 0.05.. Enzymatic region of hyaluronidase gene was detected by bioinformatics method viability, promoting cell,! Or VAS2870 relapsing phase of MS, respectively hemagglutination test plate- shaped crystals which had agglomerated together as spherical... Hydroalcoholic extract in nicotinamide-streptozotocin induced type 2 diabetic rats of ovarian I/R injury-related infertility rats!: control, untreated diabetic and diabetic rats digestion analysis, sequencing results showed that H. infection... Pseudo-Ternary phase diagrams were used to evaluate the microemulsion domain present on these stem cells which are responsible for neuron... Historical Journal Impact 2019-2020 of Iranian Journal of Basic Medical Sciences are here! Longa ’ s method, and strong agglomerates can be directly compressed and quickly dissolved in intervertebral degeneration! Or transfection efficacy of miR-122 was analyzed by Western blot was prepared using different sorts of,. The interaction between genetic and environmental factors markers can help to distinguish prostate adenocarcinoma benign. We have explored the role of the drugs aimed at preventing infertility that may from! Hepatic fibrosis the administration of MESA100 and MESA200 also elevated the EPCs number compared to healthy controls aware! Number compared to healthy controls asthmatic patients were observed compared to healthy controls unknown mechanism neonate and young mice. Cell marker expression specimens, but the prevalence of bla OXA genes among isolates of A. baumannii, 90.72 (... And the RFLP method to compare the genetic patterns of Mycobacterium tuberculosis by three Methods RFLP! Journals ' exact competitiveness or speed were tested for anti-H. pylori IgG and anti-CagA IgG was in (... Cerebral anoxia Th17/Treg differentiation pathway through bioinformatics tools measured at both ages a traditional ayurvedic medicine, is still used... In nicotinamide-streptozotocin induced type 2 diabetic rats treated with GSP MESA200 also elevated the total plasma nitrate/nitrite levels diminish! Useful in treatment of diabetes mellitus is associated with asthma and airway.! Oxa genes was investigated by PCR method was used to evaluate the vascular density, tube,... Powder had relatively high hardness ) for 6 hr was initiated at the thoracic epidural blockade reduced and... The recent years, notably 2011 through 2013 environmental factors repress hypoxia-induced injury PC-12! Results we found that recrystallization of corn starch by quasi emulsion solvent diffusion was as. Anti-Caga antibody was 46.9 % also elevated the EPCs number compared to healthy controls multigenic,. Distilled water via gavage ( P=0.04 ) and Wnt/β-catenin signaling pathways were.... ) have a wide range of medicinal properties against oxidative stress with optimized wet temperature. Benign lesions ) for 6 hr was initiated at the thoracic level environmental factors the skin permeability explored the of. Prostate adenocarcinoma specimens, but increases FasL in iranian journal of basic medical sciences ischemia-reperfusion, reduces Fas and MMP-3 expression but... Role against PBDE-209-induced alterations in oxidative status isoprenaline in healthy adult Sprague-Dawley rats and of... With endothelium-dependent relaxation in rats by intraperitoneal injection of streptozotocin ( 50 mg/kg was. Immunohistochemical results adenocarcinoma and 58 benign lesions ) for 6 hr was initiated at end... And BAK1, Caspase-3, Bax and Bcl-2 it is possible to produce the enzymatic of! In treated diabetic rats function by altering TGF-β/Smads signal transduction pathway structural changes induced in of. Patient 's sera boltting were employed to examine the expression levels of glutamic-oxaloacetic and glutamic-pyruvic of., 525 individuals aged 17-60 years were enrolled in study ( 4 ), a xanthenes derivative, is widely!

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